Differentiation of beta thalassemia trait from iron deficiency anemia by hematological indices

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Differentiation of beta thalassemia trait from iron deficiency anemia by hematological indices

OBJECTIVE We aimed at finding out reliable parameter in the differentiation of iron deficiency anemia (IDA) and beta-thalassemia trait (β-TT) in the adult population subjected to Saudi Arabian Premarital Screening Program. METHODS A total of 620 adults (age range 21-36 years) reported during February 2012 to November 2012. Tests for serum iron and ferritin were carried out in individuals show...

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Hematological Indices for Differential Diagnosis of Beta Thalassemia Trait and Iron Deficiency Anemia

Background. The two most frequent types of microcytic anemia are beta thalassemia trait ( β -TT) and iron deficiency anemia (IDA). We retrospectively evaluated the reliability of various indices for differential diagnosis of microcytosis and β -TT in the same patient groups. Methods. A total of 290 carefully selected children aged 1.1-16 years were evaluated. We calculated 12 discrimination ind...

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Evaluation of Twenty Four Discriminant Indices for Differentiating Beta-Thalassemia Trait from Iron Deficiency Anemia in Egyptians

Background: Many Red Blood Cell (RBC) indices have been developed based on mathematical formulae to discriminate beta-thalassemia trait (βTT) from iron deficiency anemia (IDA). The latter two conditions represent the most common causes of microcytic hypochromic anemia in Egypt. This study aimed To evaluate the diagnostic reliability of 24 published discriminant indices for differentiating βTT f...

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Iron-deficiency anemia and thalassemia trait differentiated by simple hematological tests and serum iron concentrations.

The diagnostic value of common hematology tests in differentiating between thalassemia trait and iron-deficiency anemia (IDA) was assessed. Serum iron concentration was included in a second stage of the diagnostic model and its predictive contribution was determined. After applying discriminant analysis to the data, minimization of Wilks's lambda (lambda) criterion was used to select the best p...

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Diagnostic reliability check of red cell indices in differentiating Iron Deficiency Anemia (IDA) from Beta Thalassemia Minor (BTT)

Introduction: Iron deficiency anemia and beta-thalassemia trait are the two most common causes of hypochromic microcytic anemia. There are some discriminating functions (DFs) formula to differentiate these two conditions based on RBC's indices which would be compared the validity of the 14 various indices in this study. Correspond...

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ژورنال

عنوان ژورنال: Pakistan Journal of Medical Sciences

سال: 2017

ISSN: 1681-715X

DOI: 10.12669/pjms.333.12098